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In some embodiments, the formulations described herein have a practical osmolarity of about 100 mOsm/L to about 1000 mOsm/L, about 200 mOsm/L to about 800 mOsm/L, about 250 mOsm/L to about 500 mOsm/L, about 250 mOsm/L to about 350 mOsm/L, about 250 mOsm/L to about 320 mOsm/L, or about 280 mOsm/L to about 320 mOsm/L

GH activates hormone-sensitive lipase in adipocytes, promoting free fatty acid release from visceral fat depots

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The spleen was carefully lifted to expose the pancreas, and 50 L of cell suspension (1 10 6 cells) was slowly injected into the pancreatic parenchyma using an insulin syringe with a needle depth of approximately 3 mm